Ttc9a
WebTTC9A deficient mammary gland showed significant increase in mammary ductal elongation and branching on estrogen and progesterone treatment, demonstrating aberration in hormone receptor signaling in absence of TTC9A.These observations suggest that TTC9A negatively regulates mammary gland development and the possibility that … Web15 rows · Mar 21, 2024 · GeneCards Summary for TTC9 Gene. TTC9 (Tetratricopeptide Repeat Domain 9) is a Protein Coding gene. Diseases associated with TTC9 include Large …
Ttc9a
Did you know?
WebAug 12, 2008 · TTC9A (1–100), which contains the first TPR domain, interacted with Tm5NM-1 to some extent but the interaction was weaker than TTC9A (1–115). Since the first TPR domain lies in residues 57–90, it is plausible that the first TPR domain is required for the interaction. WebFeb 10, 2024 · This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our privacy notice and privacy notice and
WebEmerging evidence suggests that estradiol is a potent modulator of neuroplasticity. As estradiol and neuroplasticity changes are both implicated in mood regulation, and estradiol activity is negatively regulated by TTC9A, we hypothesized that the behavioral changes induced by Ttc9a-/- is also mediated by neuroplasticity-related mechanisms. WebThe involvement of tetratricopeptide repeat domain 9A (TTC9A) deficiency in anxiety-like responses and behavioral despair through estradiol action on the serotonergic system has been reported. Emerging evidence suggests that estradiol is a potent modulator of neuroplasticity. As estradiol and neurop …
WebDC Field Value Language; dc.contributor.author: Shrestha, Smeeta: en: dc.contributor.author: Sun, Yang: en: dc.contributor.author: Lufkin, Thomas: en: dc.contributor ... WebSep 14, 2012 · TTC9A was induced by mitogens, estrogen and growth factors in breast cancer cells MCF-7 [2]. TTC9A expression is also significantly higher in breast cancer tissues than the adjacent normal tissues [17]. These indicate that TTC9A expression is positively associated with cell proliferation and the presence of growth-stimulating signals.
WebEmerging evidence suggests that estradiol is a potent modulator of neuroplasticity. As estradiol and neuroplasticity changes are both implicated in mood regulation, and …
WebApr 1, 2024 · In brief, Ttc9a-/-and wildtype female mice were subjected to ovariectomy (OVX) as reported (Lim et al., 2016; Lin et al., 2001). After a 10-day recovery period, mice were administered a subcutaneous injection of either 10 μg/kg 17-β-estradiol benzoate . Effects of Ttc9a-/-and estradiol modulation on tail suspension immobility improve our relationshipWebPrimePCR™ Template for Probe Assay: TTC9, Human Reaction: 200 x 20 µl reactions Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay. improve our healthWebTTC9A through estradiol action in emotional control. Although we know that Ttc9a-/- induces anxiety-like behavior through the effect of estradiol on serotonergic system 9, the … improve outdoor wifiWebApr 1, 2024 · We aimed to investigate the interactive roles of TTC9A and estradiol modulation on behavioral neuroplasticity. The tail suspension immobility data and brain … lithium 500%WebLi Quan, Wing Shan Yu, Smeeta Shrestha, Yu Zuan Or, Thomas Lufkin, Ying-Shing Chan, Valerie CL Lin and Lee Wei Lim (2024) TTC9A deficiency induces estradiol-mediated … improve our understandingWebNumber of male and female pups from Ttc9A KO mice crosses. There is no 13 significant difference in the male and female offspring ratios from Ttc9a+/+ X Ttc9a+/+, 14 Ttc9a+/-X Ttc9a+/-and Ttc9a-/-X Ttc9a-/- crosses. 15 16 (Table S3) Supplementary Table 3. Organ Weights of female Ttc9a KO mice at 3 weeks 17 and 6 weeks of age 18 improve outcome synonymWebMay 2009 - Sep 20123 years 5 months. Nanyang Technological University, Singapore. • Perform hands-on wet lab work to generate TTC9A mutant … lithium 4x4 off road vehicle